What You Need to Know Ginko
Table of Contents
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Introduction
What is ginkgo?
Ginkgo or Ginkgo biloba is one of the world'southward oldest living tree species. Ginkgo has been used for many years for a diverseness of medicinal purposes.
What is ginkgo extract?
Ginkgo excerpt is made from the leaves of the Ginkgo biloba tree. The leaves contain a circuitous mixture of components. The exact formulation of ginkgo extract in products available to consumers in the U.S. can vary from manufacturer to manufacturer.
Why practice some people accept ginkgo extract?
In the U.Southward., ginkgo extract is readily available to consumers as an herbal supplement. People accept it for a wide variety of wellness reasons, mostly to meliorate brain function and retention. However, clinical trials designed to assess the efficacy of ginkgo extract take not produced consistent testify of benefit. Ginkgo extract is typically taken orally. It is institute in capsules, tablets, or teas, merely may also be available in liquid extracts.
Is ginkgo extract regulated?
Ginkgo is marketed in the U.South. as a dietary supplement and regulated by the U.S. Food and Drug Administration (FDA). In general, the FDA regulations for dietary supplements are different from regulations for prescription or over-the-counter drugs. Federal police force does not crave dietary supplements to go through the same standards of premarket testing for prophylactic or efficacy as drugs intended to care for, cure, forestall, diagnose, or mitigate disease.
Why did the National Toxicology Plan (NTP) report ginkgo extract?
The National Toxicology Program conducts studies to identify the potential impairment of short and long-term exposure to some botanical dietary supplements. The nomination to study ginkgo extract came from the National Cancer Plant (NCI) because of its widespread use equally an herbal supplement and the limited data on toxicity and carcinogenicity. The ginkgo studies are part of a larger National Toxicology Programme (NTP) initiative to evaluate the rubber of a number of widely used herbal products.
What did NTP toxicity and carcinogenicity studies find?
NTP looked at the long-term furnishings of ginkgo excerpt in mice and rats. Ginkgo excerpt was given orally to the animals for up to 105 weeks. At the finish of the two-year studies, NTP found an increase in liver cancer in male and female mice, and in cancer of the thyroid gland in male person and female rats and male mice.
NTP works closely with the FDA to conduct research studies to address questions well-nigh the safety of a wide diversity of dietary supplements.
What do the NTP studies mean for humans?
NTP rodent studies on ginkgo extract may exist relevant to humans. However, these studies represent only the first pace in determining if there is a human cancer risk from taking ginkgo extract as a dietary supplement. The next steps will include identification of components in the extract that may account for the cancer findings, forth with the collection of additional information on human consumption of ginkgo excerpt.
What have some other major NIH-supported research studies looking at the health benefits of ginkgo found?
In the largest clinical trial of ginkgo to date, researchers supported by the National Institutes of Health (NIH) looked at data on more than than iii,000 people, ages 75 or older, between 2000 and 2008. Half took ginkgo, half did not. All participants in the Ginkgo Evaluation of Memory (GEM) study took tests of their thinking abilities. The researchers constitute that 120 milligrams taken twice daily was not effective in reducing the incidence of dementia, lessening cognitive decline, reducing blood pressure or hypertension, or reducing cardiovascular disease events. NIH is besides supporting boosted research studies on ginkgo.
Should I end or start taking ginkgo extract?
Consumers should exist aware that studies have non consistently demonstrated that ginkgo improves brain office. The NTP findings showing that both rats and mice develop cancer after long-term apply should as well be taken into consideration. Additionally, ginkgo has been shown to collaborate with other drugs, which tin increase or decrease their effects. Information technology is e'er important to give your wellness care provider a full picture of what you lot practice to manage your health, including taking dietary supplements. This will assist ensure coordinated and safe care.
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Additional Resources
- 5 Tips: What Consumers Need To Know About Dietary Supplements - If y'all are thinking near or are using a dietary supplement, here are five tips to consider.
- Botanical Dietary Supplements - NIH Office of Dietary Supplements
- Gingko - NIH National Eye for Complementary and Integrative Health
- FDA 101: Dietary Supplements - U.S. Food and Drug Administration
- Technical Study on Ginkgo Biloba Extract - National Toxicology Program
- Using Dietary Supplements Wisely - NIH National Middle for Complementary and Integrative Health
Related Health Topics
- Toxicology
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Source: https://www.niehs.nih.gov/health/topics/agents/ginkgo/index.cfm
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